Platelet Autoantibody Test (ITP Workup)
| Also Known as (Alias) | Platelet Flow Cytometry |
| Method | flow cytometry |
| Test Information | Idiopathic Thrombocytopenic Purpura (ITP) is a diagnosis associated with elevated platelet associated IgG, IgM or both. Positive autoantibody test results are indicative of autoimmune destruction. Positive indirect antibody test results, using patient’s plasma against normal random platelets, may indicate ITP depending upon the patient’s transfusion or pregnancy history. In approximately 85% of patients with ITP the presence of an autoantibody can be detected |
| Additional Test Information | Patients who require autoantibody testing must be platelet transfusion independent for approximately 5 days to ensure that the platelets being tested are the patient’s own platelets and not circulating donor platelets. |
| Sample Requirements | Citrate (blue top) EDTA (lavender top) |
| Requested Volume | 5cc Citrate (blue top)
EDTA (lavender top) for amount refer below ***We cannot recover sufficient platelets to perform a direct assay of antibody bound to autologous platelets. Contact Lab Supervisor for testing options |
| Sample Information | Samples must be received Monday thru Friday morning. Samples received after 10:00am on Friday or over the weekend will have to be re-drawn. |
| Shipping Information | Send whole blood at ambient temperature and should be received in the lab within 24 hours after collection
Send samples to: For additional information please see Ordering Information |
| Requisition Form | RFT- Immunogenetics/HLA and Platelet Immunology Labs |
| Transaction Code | 3640-00 |
| CPT Codes | 86022 x2, 86023 x2 |
| Test Schedule | Monday thru Friday morning |
| Turn around Time (analytic time) | 1 business day |
| Report/Results | Fax number required to receive report |