Rivaroxaban-Direct Factor Xa Inhibitor
| Also Known as (Alias) | Xarelto |
| Indications | Testing plasma level of rivaroxaban, an anticoagulant. A therapeutic range has not been determined. Levels measured in patients on therapy vary widely. If assessing steady-state levels, measurement at trough is recommended. |
| Method | Chromogenic |
| Test Information | Rivaroxaban is detected with an anti-Xa assay using a rivaroxaban-specific standard |
| Sample Requirements | Whole Blood: 3.2% Sodium Citrated (blue top) OR Frozen Plasma |
| Requested Volume | Two 5 ml 3.2 sodium citrated (blue top) tubes as whole blood OR Frozen plasma in 4 X 1mL aliquots in plastic tubes |
| Sample Information | Whole blood is preferred for testing but if it is not possible to send whole blood tubes TO ARRIVE HERE WITHIN 3 HOURS of collection then send frozen plasma. To prepare plasma centrifuge blue top tubes at 1500g for 15 minutes and remove the plasma and centrifuge a second time at 1500g for an additional 15 minutes. Aliquot approximately 1 ml of plasma into 4 plastic tubes, and freeze. |
| Shipping Information | Whole Blood: Send at ambient temperature (18-25C) and must be received within the lab in less than or equal to 3 hours after collection. Frozen Plasma: send on dry ice Send samples to: Bloodworks Northwest For additional information, please see Ordering Information |
| Requisition Form | RFT- Hemostasis Reference Laboratory |
| Transaction Code | 3220-17 |
| CPT Codes | 80299 |
| Report/ Results | Fax number required to receive report |