Hemolysis Evaluation
| Indications | This battery can be ordered for clinical scenarios that include serological evaluation for possible clinical hemolysis such as a patient with a decrease in hematocrit that is unexplained by bleeding and supporting laboratory values (LDH, indirect bilirubin, haptoglobin) are suggestive of hemolysis or a patient who is being monitored due to the presence of a red cell autoantibody or a hemolytic anemia. |
| Method | Sample will be evaluated by multiple methodologies |
| Test Information | Initial testing consist of direct and indirect antiglobulin tests (DAT, IAT) if the previous testing was non-reactive. The investigation may include an elution with PEG-IAT, antibody identification if required, common phenotyping and in rare cases, red cell separation or RBC genomic testing if evidence of transfused cells is seen in the phenotyping. |
| Sample Requirements | EDTA tube. Serum separator gel tube is not acceptable. |
| Requested Volume | 2 full 7 ml EDTA sample |
| Minimum Volume or Pediatric volume | Minimum volume: 1 full 7 ml EDTA sample Pediatric: 1 full 3 ml EDTA sample; neonate: 2 full 0.5 ml EDTA microtainers |
| Shipping Information | Ship at ambient temperature
Send samples to: |
| Requisition Form | RFT-Request for Testing Transfusion Services Immunohematology Consultation Request |
| CPT Codes | To be determined by tests performed |
| Test Schedule | Monday through Sunday |
| Turn around Time (analytic time) | TAT may vary depending on the complexity of the workup and patient status. Preliminary results available within 24 hours |
| Report/ Results | Fax number required to receive report |