Zimring Laboratory

“Curing certain diseases and mitigating the suffering they cause inspires me to carry out basic and translational research in transfusion medicine and non-malignant hematology.” James Zimring, MD, PhD

Dr. Zimring’s research lab studies both the mechanisms by which such immunizations occur and potential therapeutic interventions to either prevent or overcome it.

Immune Responses to Blood Cells

• When a recipient receives a blood transfusion, their immune system can make antibodies against the donor blood. When enough of these antibodies are formed, it can be difficult, and at times impossible, to find compatible blood for a patient. In such cases, the immune response may deprive a patient of otherwise life saving therapy.
• When a pregnant woman makes an immune response to the blood cells of her fetus, fetal death can occur.
• Some patients mount antibody responses against their own blood cells, which can result in sickness and in some cases death.

Laboratory Members